To investigate the change of erection duration measured by stopwatch with flexible dose vardenafil administered for 8 weeks in subjects with erectile dysfunction ED. Effect of levitra on sustenance of erection was an open-label, prospective, multicenter and single-arm study deed to measure the duration of erection in men with ED receiving a flexible dose of vardenafil over an 8-week treatment period.
Patients were instructed to take vardenafil 10 mg 60 min before attempting the intercourse. Vardenfil could be increased to 20 mg or decreased to 5 mg concerning patients' efficacy and safety.
Following the initial screening, patients entered a 4-week treatment-free run-in phase and 8-week treatment period, during which they were instructed to attempt intercourse at least four times on four separate days.
A total of 95 men were enrolled in 10 centers. After the 8 weeks treatment, the mean duration of erection leading to successful intercourse was statistically superior when patients were treated with vardenafil. After an 8-week treatment, the duration of erection leading to successful intercourse was 9. There were ificant benefits with vardenafil in all domains of International Index of Erectile Function.
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Secondary efficacy end points included success rate of penetration, maintaining erection, ejaculation and satisfaction were superior when patients were treated with vardenafil. There was a ificant correlation between duration of erection with other sexual factors. Also partner's sexual satisfaction was increased with vardenafil. Most adverse events were mild or moderate in severity. Vardenafil was safe and well tolerated.
Vardenafil therapy provided a statistically superior duration of erection leading to successful intercourse in men with ED with female partner. Please enable it to take advantage of the complete set of features! Clipboard, Search History, and several other advanced features are temporarily unavailable. Search: Search. Advanced Clipboard. Display options Display options. Create file Cancel. citation Subject: 1 selected item: - PubMed.
Effect of levitra on sustenance of erection (eros): an open-label, prospective, multicenter, single-arm study to investigate erection duration measured by stopwatch with flexible dose vardenafil administered for 8 weeks in subjects with erectile dysfunction
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Full text links Cite Display options Display options. Abstract To investigate the change of erection duration measured by stopwatch with flexible dose vardenafil administered for 8 weeks in subjects with erectile dysfunction ED. Seftel AD. J Urol. Epub Mar PMID: No abstract available. Rosenberg MT, et al.
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Int J Clin Pract. Clinical Trial. Duration eros adult erection: does it really matter? A randomized, double-blind clinical trial to assess the impact of vardenafil ODT on duration of erection and its correlation with patients' and partners' sexual quality of life and duration of intercourse: the VADEOPEN study.
Martin-Morales A, et al. J Sex Med. Stopwatch-assessed duration of erection: a new measure of the efficacy of erectile dysfunction treatments. Int J Impot Res. Epub Dec PMID: Review. Ohl DA, et al. Sex Med Rev. See all similar articles. Cai Z, et al. Aging Dis. References J Sex Med. Publication types Clinical Trial Actions. Multicenter Study Actions. Research Support, Non-U. Gov't Actions. MeSH terms Adolescent Actions.
Adult Actions. Aged Actions. Alcohol Drinking Actions. Asian Continental Ancestry Group Actions. Dose-Response Relationship, Drug Actions.
Ejaculation Actions. Endpoint Determination Actions. Female Actions. Humans Actions. Male Actions. Middle Aged Actions. Prospective Studies Actions. Smoking Actions. Young Adult Actions. Substances Phosphodiesterase 5 Inhibitors Actions. Vardenafil Dihydrochloride Actions. Full text links [x] Nature Publishing Group.